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Week 1 of the 2021-22 NFL regular season is set to kick off on Thursday night with a primetime clash between the defending Super Bowl champion Tampa Bay Buccaneers and America’s Team, the Dallas Cowboys.
Ahead of the start of the season, the oddsmakers shared their updated betting odds — including point spreads and over/unders — for every game on the schedule.
The Los Angeles Rams, San Francisco 49ers, and Buccaneers are the biggest favorites of the week at -7.5, while the closest game to call is a pick ’em between the Los Angeles Chargers and Washington Football Team.
Who is favored to bring home the wins in Week 1 and watch action can you get in on?
A full look at the updated Week 1 betting odds can be seen below, via BetOnline.com.
NFL Week 1 Betting Odds
Dallas Cowboys vs Tampa Bay Buccaneers (-7½)
Over/Under 52
Note: The game opened with Tampa Bay -6. The total is unchanged.
Pittsburgh Steelers vs Buffalo Bills (-6½)
Over/Under 48
Note: The game opened with Buffalo -6. The total went down 3½ points.
New York Jets vs Carolina Panthers (-5)
Over/Under 45
Note: The game opened with Carolina -4. The total has went up two points.
Jacksonville Jaguars (-1½) vs Houston Texans
Over/Under 44½
Note: The game opened with Jacksonville -1½. The total went down one point.
Arizona Cardinals vs Tennessee Titans (-3)
Over/Under 52
Note: The game opened with Tennessee -2. The total went up one point.
Los Angeles Chargers (pk) vs Washington Football Team (pk)
Over/Under 44½
Note: The game opened with Los Angeles -1. The total went down one point.
Philadelphia Eagles vs Atlanta Falcons (-3½)
Over/Under 46
Note: The line is unchanged. The total went up 2½ points.
Seattle Seahawks (-2½) vs Indianapolis Colts
Over/Under 48½
Note: The game opened with Indianapolis -2½. The total went down four points.
Minnesota Vikings (-3) vs Cincinnati Bengals
Over/Under 48
Note: The line is unchanged. The total went down one point
San Francisco 49ers (-7½) vs Detroit Lions
Over/Under 45½
Note: The line is unchanged. The total went down ½ point.
Denver Broncos (-2½) vs New York Giants
Over/Under 42
Note: The game opened with Denver -1. The total went down ½ point.
Green Bay Packers (-4½) vs New Orleans Saints
Over/Under 50½
Note: The game opened with New Orleans -3. The total went up ½ point.
Cleveland Browns vs Kansas City Chiefs (-6½)
Over/Under 53
Note: The game opened with Kansas City -5½. The total went up 1½ points
Miami Dolphins vs New England Patriots (-3)
Over/Under 43½
Note: The game opened with New England -1½. The total went down three points
Chicago Bears vs Los Angeles Rams (-7½)
Over/Under 44
Note: The game opened with Los Angles -7. The total went down two points.
Baltimore Ravens (-4½) vs Las Vegas Raiders
Over/Under 51
Note: The game opened with Baltimore -6½. The total is unchanged.
