NFL Betting Odds 2023: Opening Lines For Week 17

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The 2023-24 NFL regular season is winding down as we prepare for the penultimate week of the campaign. The Week 17 action will get underway on Thursday, December 28, when the Cleveland Browns host the New York Jets on Thursday Night Football on Prime Video.

With Week 17 just over two days away, the oddsmakers released the opening lines and point spreads for the upcoming week.

Entering the week, the San Francisco 49ers are the biggest favorite on the board, laying 13.5 points against the Washington Commanders. The Buffalo Bills, meanwhile, are listed as 12-point favorites over the New England Patriots.

The Philadelphia Eagles are the only other team to open as double-digit favorites as they are listed as 10.5-favorites over the Arizona Cardinals.

Who are all of the favorites in Week 17?

A full look at the opening lines and betting odds can be seen below, via BetOnline.ag.


NFL Week 17 Opening Lines & Betting Odds

Thursday, December 28

  • New York Jets @ Cleveland (-7)

Saturday, December 30

  • Detroit @ Dallas (-6)

Sunday, December 31

  • New England @ Buffalo (-12)
  • Atlanta @ Chicago (-3)
  • Las Vegas @ Indianapolis (-3)
  • Los Angeles Rams (-6) @ New York Giants
  • Arizona @ Philadelphia (-10½)
  • New Orleans @ Tampa Bay (-3)
  • San Francisco (-13½) @ Washington
  • Carolina @ Jacksonville (-7)
  • Miami @ Baltimore (-4)
  • Tennessee @ Houston (-3½)
  • Pittsburgh @ Seattle (-3½)
  • Los Angeles Chargers @ Denver (-6)
  • Cincinnati @ Kansas City (-7)
  • Green Bay @ Minnesota (-2½)
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