Updated NFL Week 1 Betting Odds: Point Spreads For Every Game

The NFL regular season will officially kick off on Thursday, September 7, and the oddsmakers are ready to give us a look at how the action could play out.

The season kicks off with a primetime showdown between the defending Kansas City Chiefs and Detroit Lions at Arrowhead Stadium. Despite questions about the health of star tight end Travis Kelce, the Chiefs are 4.5-point favorites.

Entering Week 1, the biggest favorite on the schedule is the Baltimore Ravens, who are 10-point favorites over the visiting Houston Texans.

The Chicago Bears, meanwhile, have the closest spread as one-point favorites at home against Green Bay.

Who are all of the favorites in Week 1?

A full look at the opening lines and betting odds can be seen below, via BetOnline.ag.

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Week 1 Opening Lines

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Thursday September 7, 2023

• Detroit Lions at Kansas City Chiefs (-4½)

Note: The Line opened at KC -7.

Sunday September 10, 2023

• Green Bay Packers at Chicago Bears (-1)

Note: The Line opened at Chicago -2½.

• Cincinnati Bengals (-2½) at Cleveland Browns

Note: The Line opened at Cincinnati -3.

• Tampa Bay Buccaneers at Minnesota Vikings (-5½)

Note: The Line opened at Minnesota -7.

• Houston Texans at Baltimore Ravens (-10)

Note: The Line opened at Baltimore -9.

• Arizona Cardinals at Washington Commanders (-7)

Note: The Line opened at Washington -3½.

• Tennessee Titans at New Orleans Saints (-3)

Note: The Line opened at New Orleans -2½.

• Philadelphia Eagles (-4) at New England Patriots

Note: The Line opened at Philadelphia -3½.

• Carolina Panthers at Atlanta Falcons (-3½)

Note: The Line opened at Atlanta -3.

• Jacksonville Jaguars (-4½) at Indianapolis Colts

Note: The Line opened at Jacksonville -3.

• San Francisco 49ers (-2½) at Pittsburgh Steelers

Note: The Line opened at SF -3.

• Las Vegas Raiders at Denver Broncos (-3½)

Note: The Line opened at Denver -1½.

• Los Angeles Rams at Seattle Seahawks (-5½)

Note: The Line opened at Seattle -4.

• Miami Dolphins at Los Angeles Chargers (-3)

Note: The Line opened at Los Angeles -3.

• Dallas Cowboys (-3) at New York Giants

Note: The Line opened at Dallas -2½.

Monday September 11, 2023 

• Buffalo Bills (-2½) at New York Jets

Note: The Line opened at Buffalo -1.