NFL Betting Odds 2022: Week 13 Opening Lines & Over/Unders

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The 2022 NFL regular season is in full swing and the start of another week is just around the corner. While there is still one game remaining in Week 12 with the Indianapolis Colts and Pittsburgh Steelers facing off on Monday Night Football, it’s never too early to look ahead.

With Week 13 just a few days away, the oddsmakers released the opening lines and over/unders for the upcoming week.

According to the opening odds, the Dallas Cowboys are the biggest favorites of the week opening as 9.5-point favorites over the Colts while the Jacksonville Jaguars at Detroit Lions has the highest projected over/under at 51 points.

Who are all of the favorites in Week 13?

A full look at the opening lines and betting odds can be seen below, via BetOnline.ag.


NFL Week 13 Opening Lines & Betting Odds

Thursday, Dec 01, 2022

  • Buffalo Bills (-5½) at New England Patriots | Over/Under: 45

Sunday, Dec 04, 2022

  • New York Jets at Minnesota Vikings (-3) | Over/Under: 41½
  • Denver Broncos at Baltimore Ravens (-9) | Over/Under: 39
  • Pittsburgh Steelers at Atlanta Falcons (-1½) | Over/Under: 41½
  • Tennessee Titans at Philadelphia Eagles (-6½) | Over/Under: 44
  • Jacksonville Jaguars at Detroit Lions (-1) | Over/Under: 51
  • Washington Commanders (-1½) at New York Giants | Over/Under: 41
  • Cleveland Browns (-6½) at Houston Texans | Over/Under: 45
  • Green Bay Packers (-2½) at Chicago Bears | Over/Under: 44½
  • Seattle Seahawks (-4½) at Los Angeles Rams | Over/Under: 42½
  • Miami Dolphins at San Francisco 49ers (-3½) | Over/Under: 46½
  • Los Angeles Chargers (-2½) at Las Vegas Raiders | Over/Under: 49
  • Kansas City Chiefs (-3) at Cincinnati Bengals | Over/Under: 51½
  • Indianapolis Colts at Dallas Cowboys (-9½) | Over/Under: 43

Monday, Dec 05, 2022

  • New Orleans Saints at Tampa Bay Buccaneers (-6½) | Over/Under: 40½
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