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The 2022 NCAA Tournament officially gets underway on Tuesday night with the opening games of the First Four. The winners will advance to The Big Dance before Wednesday’s games round out the official Round of 64 field.
Ahead of the start of the tournament, the oddsmakers released the opening lines and odds for every matchup in the First Four and Round of 64.
What are the odds for the start of March Madness?
A full look at the betting odds for the First Four and Round of 64 for the 2022 NCAA Tournament can be seen below, via SportsBetting.ag.
Opening Lines for NCAA Tournament Matchups
First Four – Tuesday
No. 16 Texas A&M Corpus-Christi vs. No. 16 Texas Southern
Spread: Texas Southern -3.5
Total: 135
No. 12 Indiana vs. No. 12 Wyoming
Spread: Indiana -3.5
Total: 132
First Four – Wednesday
No. 16 Wright State vs. No. 16 Bryant
Spread: Wright State -2
Total: 152
No. 11 Rutgers vs. No. 11 Notre Dame
Spread: Notre Dame -1
Total: 131.5
Round of 64 – Thursday
No. 5 UConn vs. No. 12 New Mexico State
Spread: UConn -6.5
Total: 133
No. 4 Arkansas vs. No. 13 Vermont
Spread: Arkansas -5
Total: 139.5
No. 1 Baylor vs. No. 16 Norfolk State
Spread: Baylor -20
Total: 137.5
No. 8 North Carolina vs. No. 9 Marquette
Spread: North Carolina -3
Total: 150.5
No. 6 Colorado State vs. No. 11 Michigan
Spread: Michigan -2.5
Total: 140.5
No. 3 Tennessee vs. No. 14 Longwood
Spread: Tennessee -17
Total: 132.5
No. 7 Murray State vs. No. 10 San Francisco
Spread: San Francisco -1.5
Total: 138
No. 2 Kentucky vs. No. 15 St. Peter’s
Spread: Kentucky -17.5
Total: 133.5
No. 8 San Diego State vs. No. 9 Creighton
Spread: San Diego State -2
Total: 119
No. 5 Iowa vs. No. 12 Richmond
Spread: Iowa -9.5
Total: 150.5
No. 4 Providence vs. No. 13 South Dakota State
Spread: Providence -1.5
Total: 148.5
No. 1 Gonzaga vs. No. 16 Georgia State
Spread: Gonzaga -23.5
Total: 148.5
No. 8 Boise State vs. No. 9 Memphis
Spread: Memphis -2.5
Total: 132
No. 4 UCLA vs. No. 13 Akron
Spread: UCLA -14
Total: 129.5
Round of 64 – Friday
No. 7 Michigan State vs. No. 10 Davidson
Spread: Michigan State -2
Total: 141
No. 2 Duke vs. No. 15 CS Fullerton
Spread: Duke -17.5
Total: 141.5
No. 7 USC vs. No. 10 Miami (FL)
Spread: USC -1.5
Total: 141
No. 2 Auburn vs. No. 15 Jacksonville State
Spread: Auburn -16.5
Total: 139
No. 6 LSU vs. No. 11 Iowa State
Spread: LSU -4.5
Total: 125
No. 3 Wisconsin vs. No. 14 Colgate
Spread: Wisconsin -7.5
Total: 140
No. 6 Texas vs. No. 11 Virginia Tech
Spread: Virginia Tech -1
Total: 124.5
No. 3 Purdue vs. No. 14 Yale
Spread: Purdue -15.5
Total: 144.5
No. 5 Houston vs. No. 12 UAB
Spread: Houston -8.5
Total: 136.5
No. 4 Illinois vs. No. 13 Chattanooga
Spread: Illinois -7
Total: 136.5
No. 7 Ohio State vs. No. 10 Loyola-Chicago
Spread: Loyola-Chicago -1.5
Total: 133
No. 2 Villanova vs. No. 15 Delaware
Spread: Villanova -15.5
Total: 133
No. 3 Texas Tech vs. No. 14 Montana State
Spread: Texas Tech -15.5
Total: 130
No. 8 Seton Hall vs. No. 9 TCU
Spread: Seton Hall -1
Total: 130
